PlavixGeneric (Clopidogrel) keeps the platelets in your blood from coagulating (clotting) to prevent unwanted blood clots that can occur with certain heart or blood vessel conditions. Generic Plavix (Clopidogrel) is used to lessen the chance of heart attack or stroke. Generic Plavix (Clopidogrel) is used for reducing the risk of stroke or heart attack in patients who have already had a heart attack or stroke, or have other circulatory problems due to narrowing and hardening of the arteries. Generic Plavix (Clopidogrel) is indicated for the reduction of atherothrombotic events.
Brand Name: Plavix
Geneirc Name: Clopidogrel
Drug Uses
Generic Plavix (Clopidogrel) is used to prevent and reduce the risk of stroke or heart attack in patients who have already had a heart attack or stroke, or have other circulatory problems due to narrowing and hardening of the arteries. Generic Plavix (Clopidogrel) is a platelet aggregation inhibitor. Generic Plavix (Clopidogrel) works by slowing or stopping platelets from sticking to blood vessel walls or injured tissues.
Manufacture By : Generic Plavix (Clopidogrel) is manufactured by Zydus Cadila, Dr. Reddy`s Laboratories Ltd, Ranbaxy and Lupin.
Available in 75 mg tablet form.
Zydus Cadila, Dr. Reddy`s Laboratories Ltd, Ranbaxy and Lupin manufacturing strengths have established it as a producer of world-class generics, branded generics and a major supplier of its range of Active Pharmaceutical Ingredients World-Wide.
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Prescription Required: No
Drug Class and Mechanism
Generic Plavix (Clopidogrel) is an inhibitor of platelet aggregation that is, a drug that inhibits the ability of platelets to clump together as part of a blood clot. A variety of drugs that inhibit platelet function have been shown to decrease morbid events in people with established cardiovascular atherosclerotic disease as evidenced by stroke or transient ischemic attacks, myocardial infarction, unstable angina or the need for vascular bypass or angioplasty. This indicates that platelets participate in the initiation and/or evolution of these events and that inhibiting them can reduce the event rate. The risk of heart attacks and strokes (which usually are caused by blood clots) is increased in patients with a recent history of stroke or heart attack and patients with peripheral vascular disease. (Peripheral vascular disease is the same as atherosclerotic arterial disease or "hardening" of the arteries in which the arteries become narrowed. It frequently occurs in the legs and often causes claudication or pain in the legs upon walking). Generic Plavix (Clopidogrel) is used to reduce the risk of heart attacks and strokes in this patients.Generic Plavix (Clopidogrel) were approved by the FDA in 1997.
How Taken
Adults: Take Generic Plavix (Clopidogrel) exactly as directed by your doctor. The usual dose is 75 milligrams once a day. A person with unstable angina first dose is usually increased to 300 milligrams as an extra boost. Take each dose with a full glass of water. Generic Plavix (Clopidogrel) can be taken with or without food.
Children: The safety and effectiveness of Generic Plavix have not been established in children.
Missed Dose
Do not take a double dose of this medication. Take the missed dose as soon as you remember. However, if it is almost time for the next dose, skip the missed dose and take only the next regularly scheduled dose.
Storage
Store Generic Plavix at room temperature at a range of 15 to 25 degree C. Keep away from moisture and heat.
Warnings/Precautions
- Tell your doctor that you are taking this medication before having any surgical procedures.
- Do not take aspirin, ibuprofen (Motrin, Advil, Nuprin, others), naproxen (Aleve, Anaprox, Naprosyn, others), ketoprofen (Orudis, Orudis KT, Oruvail), indomethacin (Indocin), nabumetone (Relafen), oxaprozin (Daypro), or other non-steroidal anti-inflammatory medications (NSAIDs) without first talking to your doctor.
- It may take longer than usual for you to stop bleeding, even from minor wounds.
- Tell your doctor about any unusual bleeding or bruising that you experience.
- Studies have shown that clopidogrel appears in breast milk, Because of a potential for side effects in the nursing infant, the physician must weigh the potential benefits and possible risks before prescribing clopidogrel in nursing mothers.
Possible Side Effects
- The tolerability of clopidogrel is similar to that of aspirin.
- Diarrhea, rash, or itching occurs in approximately 1 in 20 persons taking clopidogrel.
- Clopidogrel rarely causes a condition called thrombotic thrombocytopenic purpura (TTP, TTP is a serious condition in which blood clots form throughout the body).
- Blood platelets, which participate in clotting, are consumed, and the result can be bleeding because enough platelets are no longer left to allow blood to clot normally.
- Abdominal pain also occurs in about 1 in 20 persons, but it is less frequent than with aspirin.
- If you experience any of the following serious side effects, stop taking clopidogrel and seek emergency medical attention or notify your doctor immediately:
• an allergic reaction (difficulty breathing; closing of the throat; swelling of the lips, tongue, or face; or hives);
• severe headache, confusion, or dizziness;
• bloody (or black) vomit or stools;
• unexplained bruising or bleeding; or
• Bleeding nose.
More Information
- Generic Plavix is to be used only by the patient for whom it is prescribed.
- Do not share it with other people.
- Patients should be told that it may take them longer than usual to stop bleeding, that they may bleed more easily when they take Generic Plavix or Generic Plavix combined with aspirin, and that they should report any unusual bleeding to their physician.
- Patients should inform physicians and dentists that they are taking Generic Plavix and/or any other product known to affect bleeding before any surgery is scheduled and before any new drug is taken.
- If you have any questions about Generic Plavix, please talk with your doctor, pharmacist, or other health care provider.
- If your symptoms do not improve or if they become worse, check with your doctor.