Lipitor Generic (Atorvastatin calcium) is a cholesterol-lowering drug also known as a "statin." Atorvastatin is used to lower cholesterol and triglyceride (fat-like substances) levels in the blood. Lowering high cholesterol and triglycerides in certain patients Generic Lipitor also increase high-density lipoprotein (HDL, "good") cholesterol levels. It is used along with an appropriate diet. Generic Lipitor is used to reduce the risk of heart attack, stroke, chest pain caused by angina, or blood vessel blockage in patients. Using this medicine may help prevent harmful low-density lipoprotein (LDL) cholesterol (such substances clogs the blood vessels) out of the blood and by limiting the body's ability to form new LDL cholesterol.
Generic Lipitor ( Atorvastatin ) is an HMG-CoA reductase inhibitor (also known as a statin) used in combination with a low-cholesterol and low-fat diet to lower cholesterol and triglyceride levels and to raise good cholesterol (HDL) levels in your blood.
Generic Lipitor is used with diet changes (restriction of cholesterol and fat intake) to reduce the amount of cholesterol and certain fatty substances in your blood. Accumulation of cholesterol and fats along the walls of your arteries (a process known as atherosclerosis) decreases blood flow and, therefore, the oxygen supply to your heart, brain, and other parts of your body. Lowering your blood level of cholesterol and fats may help to prevent heart disease, angina (Chest pain), strokes, and heart attacks.
Brand Name:
Lipitor
Generic Name: Atorvastatin Calcium
Manufacture By:
Lipitor Atorvastatin calcium is manufactured by Zydus Cadila, Cipla, Ranbaxy. (Zydus Cadila, Cipla, Ranbaxy manufacturing strengths have established it as a producer of world-class generics, branded generics and a major supplier of its range of Active Pharmaceutical Ingredients World-Wide).
Lipitor Atorvastatin Calcium is available as 10 mg,20 mg and 40 mg tablet form.
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Prescription Required: No
Drug Uses
Lipitor Atorvastatin calcium is used with diet changes (restriction of cholesterol and fat intake) to reduce the amount of cholesterol and certain fatty substances in your blood. Accumulation of cholesterol and fats along the walls of your arteries (a process known as atherosclerosis) decreases blood flow and, therefore, the oxygen supply to your heart, brain, and other parts of your body. Lowering your blood level of cholesterol and fats may help to prevent heart disease, angina (Chest pain), strokes, and heart attacks.
How Lipitor Atorvastatin calcium works (Drug Class and Mechanism)?
Lipitor Atorvastatin calcium is an oral drug that lowers the level of cholesterol in the blood. Lipitor Atorvastatin calcium is a selective inhibitor of HMG-CoA reductase, the enzyme that converts 3-hydroxy-3-methylglutaryl-coenzyme A to mevalonate, a precursor of cholesterol. Cholesterol and triglycerides circulate in the bloodstream as part of lipoprotein complexes. With ultracentrifugation, these complexes separate into HDL (high-density lipoprotein), IDL (intermediate-density lipoprotein), LDL (low-density lipoprotein), and VLDL (very-low-density lipoprotein) fractions. Triglycerides (TG) and cholesterol in the liver are incorporated into VLDL and released into the plasma for delivery to peripheral tissues. LDL is formed from VLDL and is catabolized primarily through the high-affinity LDL receptor. It causes dose dependent lowering of LDL cholesterol and reduces hepatic synthesis of very low density lipoprotein (VLDL) and lowers plasma triglyceride levels. It also increases high density lipoprotein (HDL) levels. It also exerts antioxidant property.
Absorption: Lipitor Atorvastatin drug readily absorbed orally, Distribution: Lipitor Atorvastatin drug distributed in a highly protein bound form, Metabolism: Lipitor Atorvastatin drug metabolized in liver in to active metabolite, Excretion: Lipitor Atorvastatin drug excreted mainly through bile.
How Taken
Take Lipitor Atorvastatin pills with a full glass of water. Lipitor Atorvastatin pills can be taken with or without food.
Lipitor Atorvastatin pills is usually taken once a day. Try to take your dose at the same time each day. Follow your doctor's instructions.
Your doctor may start you on a low dose of Lipitor Atorvastatin pills and gradually increase your dose. Continue to take Lipitor Atorvastatin pills even if you feel well. Do not stop taking Lipitor Atorvastatin pills Lipitor without talking to your doctor. Eat a low-fat, low-cholesterol diet.
Missed Dose
Do not take a double dose of Lipitor Atorvastatin pills medication unless otherwise directed by your doctor. Take the missed dose as soon as you remember. However, if it is almost time for the next regularly scheduled dose, skip the missed dose and take the next one as directed.
Storage
Store Lipitor Atorvastatin pills at room temperature at a range of 15 to 25 degree C. Keep Lipitor Atorvastatin pills medication out of reach of children.
What are the Warnings / Precautions of Lipitor Atorvastatin pills?
- Before taking to Lipitor Atorvastatin pills first talk to your Physician Monitor hepatic function tests and lipid levels before and periodically during therapy and stop drug if there is marked elevation of creatinine phosphokinase level.
- History of liver diseases.
- Alcoholics.
- In severe adverse effects and fever.
- Lipitor Atorvastatin pills is in the FDA pregnancy category X. This means that Lipitor Atorvastatin pills is known to cause birth defects if it is taken during pregnancy.
- Do not take Lipitor Atorvastatin pills if you are pregnant or could become pregnant during treatment.
- It is not known whether Lipitor Atorvastatin pills passes into breast milk.
- Do not take Lipitor Atorvastatin pills medication without first talking to your doctor if you are breast-feeding a baby.
Possible Side Effects
Although side effects from Lipitor Atorvastatin pills are not common, they can occur. Tell your doctor if any of these symptoms are severe or do not go away:
1.Headache 2.Dizziness 3.Insomnia 4.Alopecia 5.Anorexia 6.Abdominal discomfort 7.Heart burn 8.Abdominal pain 9.Nausea 10.Dyspepsia 11.Flatulence 12.Constipation 13.Abnormal liver function tests 14.Rash 15.Pruritus 16.Fatigue 17.Myositis 18.Chest pain 19.Impotence 20.Myopathy 21.Upper respiratory tract infections
If you experience any of the following symptoms, call your doctor immediately: muscle pain, tenderness, muscle cramps or weakness with or without a fever.
More Information
Contact your doctor immediately if you experience unexplained muscle pain, tenderness, or weakness, especially if accompanied by a fever or flulike symptoms or yellowing of the skin or eyes, abdominal pain, unexplained fatigue, dark colored urine or pale colored stools. These may be early symptoms of muscle or liver problems. Rare cases of muscle problems and liver problems have been associated with the use of atorvastatin and other similar medicines.