Why is Diflucan prescribed?
Diflucan is used to treat fungal infections called candidiasis (also known as thrush or yeast infections). These include vaginal infections, throat infections, and fungal infections elsewhere in the body, such as infections of the urinary tract, peritonitis (inflammation of the lining of the abdomen), and pneumonia.
Diflucan is also prescribed to protect against candidiasis in some people receiving bone marrow transplants, and is used to treat meningitis (brain or spinal cord inflammation) caused by another type of fungus.
In addition, Diflucan is now being prescribed for fungal infections in kidney and liver transplant patients, and fungal infections in patients with AIDS.
Brand Name: Diflucan
Generic Name: Fluconazole
Manufacture By: Glenmark Laboratories Limited (Glenmark Laboratories Limited manufacturing strengths have established it as a producer of world-class generics, branded generics and a major supplier of its range of Active Pharmaceutical Ingredients world-wide).
Diflucan is available as 50mg, 100mg, 150mg and 200mg.
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Prescription Required: No
Which are the indication Diflucan Flucanazol is prescribed?
- Oropharyngeal and esophageal candidiasis. In open noncomparative studies of relatively small numbers of patients, Fluconazole was also effective for the treatment of Candida urinary tract infections, peritonitis, and systemic Candida infections including candidemia, disseminated candidiasis, and pneumonia.
- Vaginal candidiasis (vaginal yeast infections due to Candida).
- Oropharyngeal and esophageal candidiasis; vaginal candidiasis; prevention of candidiasis in bone marrow transplant; Cryptococcal meningitis.
Dosage: For fungus infections: Adults-150 milligrams (mg) as a single dose to treat vaginal yeast infections.
How Diflucan Flucanazol work (Mode of Action)?
Fluconazole is a highly selective inhibitor of fungal cytochrome P-450 sterol C-14 alpha-demethylation. Mammalian cell demethylation is much less sensitive to Fluconazole inhibition. The subsequent loss of normal sterols correlates with the accumulation of 14 alpha-methyl sterols in fungi and may be responsible for the fungistatic activity of Fluconazole.
What are the possible side effects of Fluconazole - (Generic Diflucan)?
The following are some of the common side effects of Flucanazol- generic Diflucan: an allergic reaction (difficulty breathing; closing of the throat; swelling of the lips, tongue, or face; or hives); liver damage (pale stools, yellowing of the skin or eyes, abdominal pain, unusual fatigue, or dark urine); or a rash.
Other, less serious side effects may be more likely to occur. If you experience any of the following side effects, continue taking Fluconazole - (Generic Diflucan) and talk to your doctor: nausea, vomiting, or abdominal pain; diarrhea; headache; dizziness; fatigue; or itching. Side effects other than those listed here may also occur. Talk to your doctor about any side effect that seems unusual.
What are the drug(s) which may interact with may interact with Flucanazol- generic Diflucan?
The following are some of the Drugs which may have some interactions with Flucanazol- generic Diflucan like:
bosentan, cilostazol, cisapride, cyclosporine, dofetilide, doxercalciferol, certain medicines for anxiety or difficulty sleeping, medicines for diabetes that are taken by mouth, medicines for high cholesterol such as atorvastatin, fluvastatin, lovastatin, or simvastatin, medicines for yeast or fungal infections: paricalcitol, phenytoin, pimozide, ramelteon, rifabutin, rifampin, tacrolimus, terfenadine, warfarin, water pills. Consult with your doctor if you are taking any of the above mentioned drug before starting Flucanazole Diflucan treatment.
What happens if I miss a dose?
Take the missed dose as soon as you remember. If it is almost time for your next dose, skip the missed dose and take the medicine at your next regularly scheduled time. Do not take extra medicine to make up the missed dose.
To store this medicine: Keep out of the reach of children.
Store away from heat and direct light.
Do not store the capsule or tablet form of this medicine in the bathroom, near the kitchen sink, or in other damp places. Heat or moisture may cause the medicine to break down.
Warning And Precauctions?
- Ketoconazole may cause your eyes to become more sensitive to light than they are normally. Wearing sunglasses and avoiding too much exposure to bright light may help lessen the discomfort.
- Liver problems may be more likely to occur if you drink alcoholic beverages while you are taking ketoconazole. Alcoholic beverages may also cause stomach pain, nausea, vomiting, headache, or flushing or redness of the face.
- These medicines should not be taken with astemizole (e.g., Hismanal), cisapride (e.g., Propulsid), dofetilide (e.g., Tikosyn) or terfenadine (e.g., Seldane) . Doing so may increase the risk of serious side effects affecting the heart.